The USD's presence state is disconnected and displays the following error:
As a result, Agents cannot set their status to 'available' to service chats.
Live Assist must be added to the Trusted Sites list of Internet Explorer. Also add the Live Assist URLs to any other lists maintained by other security applications that may prevent access from the agent's machine to the Live Assist Service.
Live Assist Service URL will be in the form of:
You can find the appropriate Service URL for you organization by looking in the Dynamics 365 Live Asssit Chat Settings:
Please read: Steps to update IE's Trusted Sites